| Product dosage: 100mg | |||
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| Package (num) | Per pill | Price | Buy |
| 60 | $0.88 | $53.02 (0%) | 🛒 Add to cart |
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Trazodone: Effective Depression and Insomnia Treatment - Evidence-Based Review
Trazodone hydrochloride is a serotonin antagonist and reuptake inhibitor (SARI) antidepressant medication chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Initially developed in the 1960s by Angelini Research Laboratories in Italy, trazodone received FDA approval in the United States in 1981 and has since become one of the most prescribed medications for depression and off-label uses, particularly insomnia. Its unique pharmacological profile—combining serotonin reuptake inhibition with 5-HT2A and 5-HT2C receptor blockade—creates a distinct clinical effect different from SSRIs, making it particularly valuable for patients who cannot tolerate other antidepressants or who have comorbid sleep disturbances.
desyrel
Let me walk you through what we’ve learned about Desyrel over the years - this isn’t the polished monograph you’d find in a package insert, but rather the real clinical experience we’ve accumulated since it first appeared in our formulary. Desyrel (trazodone hydrochloride) presents one of those interesting cases where a medication’s off-label use sometimes overshadows its original indication. Initially developed as an antidepressant in the 1960s by Angelini Research Laboratories, this serotonin antagonist and reuptake inhibitor (SARI) has carved out multiple therapeutic niches that continue to surprise even seasoned prescribers.
malegra dxt plus
Malegra DXT Plus represents a significant advancement in addressing complex male sexual health concerns, particularly for patients presenting with both erectile dysfunction and premature ejaculation. This combination therapy integrates sildenafil citrate, dapoxetine, and trazodone in a single formulation, creating what we’ve observed to be a more comprehensive approach than single-agent therapies. The development journey wasn’t straightforward - our team initially debated whether combining three mechanisms was overkill or whether we’d create more side effects than benefits.
melatonin
Melatonin, an endogenous neurohormone synthesized primarily by the pineal gland, represents one of the most significant chronobiotic substances in clinical practice. Its molecular structure, N-acetyl-5-methoxytryptamine, belies its profound influence on circadian physiology. What began as a simple sleep aid has evolved into a sophisticated therapeutic agent with applications spanning jet lag, shift work disorder, and even oncology support. The transition from prescription-only to over-the-counter status in many markets has created both opportunities and challenges in its appropriate clinical utilization.
Sinequan: Multimodal Therapeutic Agent for Depression and Insomnia - Evidence-Based Review
Sinequan, known generically as doxepin, is a tricyclic antidepressant (TCA) that has been a cornerstone in psychopharmacology for decades. Initially approved for depression, its utility has expanded significantly due to its potent antihistaminic properties, particularly at the H1 receptor. This has led to its widespread off-label use for chronic urticaria, pruritus, and especially insomnia, where low doses are remarkably effective for sleep maintenance. The drug’s multifaceted mechanism—combining serotonin and norepinephrine reuptake inhibition with strong histamine blockade—makes it unique among older agents.
unisom
Unisom represents one of those interesting cases where an over-the-counter sleep aid actually contains two completely different active ingredients depending on which formulation you purchase. Most consumers don’t realize they’re essentially getting different medications when they pick up “Unisom” - there’s the doxylamine succinate version and the diphenhydramine hydrochloride version. Both are first-generation ethanolamine antihistamines, but they have slightly different pharmacokinetic profiles that can matter clinically. I remember when we first started recommending these to patients in the sleep clinic back in the early 2000s, we had to be really careful about which one we suggested.
a ret gel
Product Description: A Ret Gel represents a significant advancement in topical retinoid therapy, combining pharmaceutical-grade tretinoin with a sophisticated hydrogel delivery system. This medical device/drug combination product addresses one of the biggest challenges in dermatological treatment: delivering effective concentrations of retinoids while minimizing the irritation that often limits patient adherence. The hydrogel matrix creates a controlled-release environment that maintains tretinoin stability and enhances skin penetration compared to traditional cream or gel formulations.
Abana: Comprehensive Cardiovascular and Stress Support - Evidence-Based Review
Abana is an Ayurvedic herbal formulation primarily used in cardiovascular health management, though its applications extend to stress reduction and metabolic support. Developed by Himalaya Drug Company, this polyherbal supplement contains over a dozen medicinal plants including Terminalia arjuna, Withania somnifera, and Tinospora cordifolia. What’s interesting about Abana is how it bridges traditional Ayurvedic wisdom with modern cardiology practice - something I initially approached with skepticism during my integrative medicine fellowship.
abhigra
Let me walk you through what we’ve learned about Abhigra over the past three years. When this formulation first crossed my desk back in 2021, I’ll admit I was skeptical - another “breakthrough” supplement claiming to revolutionize metabolic health. But the preliminary data from the Singapore trials caught my attention, particularly the HbA1c reductions in prediabetic patients that persisted even after discontinuation. Abhigra: Comprehensive Metabolic Support Through Advanced Botanical Synergy - Evidence-Based Review